Bibliografía recomendada:



Clinical Aspects of Immunology
Third Edition
P.G.H. Gell, R.R.A. Coombs and P.J. Lachmann
Blackwell Scientific Publications
(Para conocer los artículos originales acerca de mecanismos de daño inmunológico descritos por estos autores).

Immunological Diseases
Fourth Edition
Max Samter Editor
Little, Brown and Company

Pathologic Basis of Disease.
Ramzi S. Cotran, Vinay Kumar and Stanley L. Robbins
Fourth Edition
W.B. Saunders Company

Ivan Roitt, Jonathan Brostoff and David Male.
Second Edition
Churchill Livingstone
Edinburgh, London and Melbourne
Gower Medical Publishing London New York.

Cellular and Molecular Immunology
First Edition
Abul K. Abbas, Andrew H. Lichtman, Jordan S. Pober.
HBJ International Edition
W.B. Saunders

Advanced Immunology .
David Male, Brian Champion, Anne Cooke, Michael Owen.
Second Edition
J.B. Lippincoll Company,Philadelphia.
Gower Medical Publishing,London,New York.

Basic and Clinical Immunology
Seventh Edition
Daniel P. Stites and Abba I. Terr
Appleton & Lange

Primer on Allergic and Immunologic Diseases.
Prepared by the American Academy of Allergy and Immunology
Richard D. de Shazo Editor
David L. Smith Associate Editor
Published in a special issue of JAMA
Journal of the American Medical Association.
November 1992

Special Issue of Scientific American
Vol.269 No.3
Sept. 1993

Mechanisms of Microbial Diseases
Second Edition
Moselio Schaechter, Gerald Medoff and Barry I. Eisenstein
Williams & Wilkins

Artículos complementarios seleccionados por tema y año:


Young,J.D.,Cohn,Z.A. and Podack, E. R. : The ninth component of complement and the pore forming protein (Perforin 1) from cytotoxic T Cells. Structural, Immunological and Functional similarities. Science 233:184-189, 1986.

Till,G.O. and Ward,P.A.: Systemic complement activation and acute lung injury. Federation Proceedings Vol 45 No.1 January 1986

Brown,E.J. : Complement receptors and phagocytosis. Current Opinion in Immunology 3: 76-82, 1991

2. Inflamación:

Ryan,G.B. and Majno,G.: Acute inflammation. A review. American Journal of Pathology Vol.86 No.1, pp.185-249 Jan 1977

Weissmann,G.: Leukocytes as Secretory Organs of Inflammation
Hospital Practice, pp. 53-62. Sept. 1978

Larsen,G.L. and Henson,P.M.: Mediators of inflammation. Annu. Rev.Immunol Vol.1 pp.335-259, 1983.

Ford-Hutchinson,A.W. : Leucotriene involvement in pathologic processes.J. Allergy Clin.Immunol.Vol.74,No.3,part.2. pp437-440. Sept.1984

Piper,P.J.: The Evolution and future horizons of research on the metabolism of arachidonic acid by 5-lipoxygenase.J. Allergy Clin.Immunol.Vol.74,No.3,part.2. pp 441-448. Sept.1984

Davies,P., Bailey,P.J. and Goldenberg, M.M.: The role of arachidonic acid oxygenation products in pain and inflammation. Annu. Rev.Immunol Vol.2 pp.235-257, 1984.

Boxer,G.J., Curnute, J.T and Boxer,L.A.: Polymorphonuclear Leukocyte Function .Hospital Practice pp.69-90 March 1985

Fajardo,L.F.: The complexity of endotelial cells .A.J.C.P. pp.241-249.Aug. 1989

Rot.A.: Chemokines link the two steps of leukocyte adhesion to endothelium. The Immunologist 1/5 pp145149, 1993

Polla,B.S.,Maridonneau-Parini,I. and Donati, Y.R.A.: Oxygen Free Radicals in Inflammation and Allergy. ACI News 3/2 pp 59-62. 1993

3. Inmunología básica:

Rouse,R. Reichert,R.,Gellatin,M.,Weissman,I and Butcher,E.: Localization of Lymphocyte subpopulations in Peripheral Lymphoid Organs: Directed Lymphocyte migration and segregation into specific Microenvironments. The American Journal of Anatomy 170:391-405,1984

Ford,W.L., Allen,T.D., Pitt,M.A., Smith,M.E. and Stoddart,R.W.: The Migration of lymphocytes across specialized vascular endothelium: Physical and chemical conditions influencing the surface morphology of lymphocytes and their ability to enter lymph nodes. The American Journal of Anatomy 170:377-390,1984

Dorshkind,K.: B-cell differentiation. Immunology Today,Vol 7,No.11,pp.322-324,1986

Von Boehmer,H.: The selection of the alpha-beta heterodimeric T cell receptor for antigen. Immunology Today, Vol 7, No.11, pp.333-336, 1986

Duvall,E. and Wyllie,A.H.: Death and the cell. Immunology Today, Vol 7, No.4, pp.115-119, 1986

Finnegan,A. and Berzofsky,A.J.: Antigen Recognition by T Cells
Immunology Today, Vol 7, No.11, pp.317-319, 1986

Dinarello,C.A.and Mier,J.W.: Lymphokines. New England Journal of Medicine 317:940-945, 1987

Lafferty, K.J.: The Immunologic Network.Transplantation Proceedings, Vol XX, No.2, Suppl.2 (April) pp13-26, 1988

Corottini,J.C. and MacDonald,H.R.: The Cellular Basis of T cell Memory. Annual Review of Immunology 7:77-89, 1989

Grey,H.M.,Sette,A. and Buus,S.: How T Cells see antigen. Scientific American pp.56-64 Nov.1989.

Treadwell,T.L.: Bacteriemia por gramnegativos. Puesta al día
Hospital Practice (Ed. Español) Vol. 4 Num.1 pp 23-33, Enero 1989

Springer,T.A.: Adhesion receptors of the immune System. Nature,Vol.346,pp. 425-434, Aug.1990

Dupuy,P.,Heslan,M., Fraitag,S., Hercend,T., Dubertret,L. and Bagot,M.: T-Cell gamma/delta bearing lymphocytes in normal and Inflammatory Human skin. The Journal of Investigative Dermatology Vol.94,No.6 pp. 764-768 June 1990.

Blackman,M. Kappler,J. and Marrack,P.: The role of T cell receptor in positive and negative selection of developing T cells.
Science Vol 248, pp 1335-1341, June 1990

Haas,W., Kaufman,S. and Martinez,C.: The development and function of gamma/delta T Cells. Immunology Today, Vol 11, No.10, pp.340-343, 1990

Coffman,R.L.: Heterogeneidad de las células T facilitadoras y patrones de respuesta inmunitaria.
Hospital Practice (Ed. Español) Vol.5 Num.3 pp 57-71, Marzo 1990

Hammerling,G.J. and Moreno,J.: The function of the invariant chain in antigen presentation by MHC class II molecules. Immunology Today, Vol 11, No.10, pp.337-339, 1990

Noelle,R.J. and Snow,E.C.: Cognate interactions between helper T cells and B cells. Immunology Today, Vol.11, No.10, pp.361-367, 1990

Posnett,D.N.: Allelic variations of human TCR V gene products. Immunology Today Vol.11, No.10, pp. 368-373, 1990

Kuziel,W.A. and Greene,W.C.: Interleukin-2 and the IL-2 Receptor: New Insights into Structure and Function. The Journal of Investigative Dermatology Vol.94, No.6 Supplement. pp.27S-32S June 1990

Smith,K.A.: Inteleukin-2. Scientific American pp.26-33 March 1990

Marrack,P. and Kappler,J.: The Staphylococcal Enterotoxins and their relatives. Science Vol 248, pp. 705-711, May 1990

Ewijk W.van : T cell differentiation is influenced by thymic microenvironments. Ann. Rev. Immunol 9: 591-615, 1991

Herman,A.,Kappler,J.W.,Marrak,P. and Pullen,A.M.: Superantigens: Mechanism of T-cell Stimulation and Role in Immune Responses. Annu. Rev.Immunol 9:745-72, 1991.

Brodsky,F. and Guagliardi,L.E.: The Cell Biology of Antigen Processing and Presentation. Annu. Rev. Immunol 9:707-744, 1991

Allison,J.P. and Havran,W.L.: The Immunobiology of T cells with invariant gamma/delta antigen receptors. Annu. Rev. Immunol 9:679-705, 1991

Perussia,B.: Lymphokine-activated killer cells, natural killer cells and cytokines. Current Opinion in Immunology 3: 49-55, 1991

Rubin,B., Geisler,G., Caspar,S. and Arnaud,J.: The indispensable CD2-CD3 Molecules: A Key to Cell Differentiation and Functional Activation. Scand.J. Immunol,36:1-6,1992

Sen,J., Bossu,P., Burakoff,S.J. and Abbas, A.K.: T cell surface Molecules regulating noncognate B Lymphocyte Activation. Role of CD2 and LFA-1. The Journal of Immunology Vol 148, pp.1037-1042, Feb 1992

Rietschel,E.T. and Brade,H.: Bacterial Endotoxins. Scientific American. pp 26-33 August 1992.

Sissons J.G.P.: Superantigens and Infections Disease.The Lancet 341:1627-1628, 1993.

Dannenberg,A.M.: Inmunopatogenia de la Tuberculosis Pulmonar. Hospital Practice (Ed. Español) Vol. 8 Num.6 pp.45-53, Junio-Julio 1993

Wyss-Coray,T. and Pichler,W.J.: The Human T Cell as an Antigen Presenting cell . ACI News 5/4 1993

Du Bois, R.M. Cytokines. Thorax Vol.48 pp. 659-853, 1993

4. Mecanismos de daño inmunológico:

Foreman, J.C. :Peptides and neurogenic inflammation. British Medical Bulletin Vol.43, No.2, pp.386-400, 1987

Slavin,R.G. y Ducomb, D.F.: Dermatitis de contacto alérgica. Hospital Practice (Ed. Español) Vol. 4 Num.9 pp 31-42, Enero 1989

Romagnani,S. and Ricci,M.: Present views on the regulation of human IgE Synthesis. Aci News 2/6 1990.

Galli,S.J., Gordon,J.R. and Wershil,B.K.: Cytokine production by mast cells and basophils. Current Opinion in Immunology 3: 865-873,1991

Ishizaka,K.: Atopic Allergy and other Hypersensitivities. Current Opinion in Immunology 3: 839-840, 1991

de Vries, J.E., Gauchat,J.F., Aversa,G.G., Punnonen,J., Gascan,H. and Yssel, H.: Regulation of IgE synthesis by cytokines. Current Opinion in Immunology 3: 851-858, 1991

Berman,J.S. and Weller,P.F.: Airway eosinophils and lymphocytes in asthma. Am. Rev. Respir. Dis. 145:1246-1248, 1992

Lee,T.H. Precipitating factors of asthma. British Medical Bulletin Vol.48,No.1,pp.169-178, 1992.

Pueringer,R.J. and Hunninghake,G.W.: Inflammation and airway reactivity in asthma. Am. J. of Medicine Vol.92 (suppl 6A0 pp 32-38.June 1992.

Bousquet,J.,Chanez,P.,Godard,P and Michel,F.B. : Is Asthma a Disease that Remodels the Airways? ACI News 5/1, pp.5-8,1993

van Wijk,R.G. and Fokkens, W. J. : Allergy of the upper respiratory tract. ACI News 5/3 pp.69-70 1993

van der Zee J.S. and Koenderman, L.: Allergy of the lower respiratory tract.The role of T lymphocytes and Eosinophils. ACI News, 5/3,pp.71-73 1993

Canonica, G.W., Pronzato,C., Fiorino,N., Ciprandi,G. and Bagnasco, M.: Adhesion molecules. A review of their clinical roles in allergic Inflammation. ACI news 5/3 pp 80-84 1993

Schlievert,P.M.: Role of superantigens in human disease. The Journal of Infectious Diseases Vol.167 pp 997-1002, 1993.

LeRoy,E.C.: Las vasculitis sistémicas. Hospital Practice (Ed. Español) Vol. 8 Num.1 pp 41-49, Enero 1993

5. Tolerancia inmunológica.

Nossal,G.J.V.: Cellular Mechanisms of Immunologic Tolerance. Ann.Rev.Immunol 4: 33-52,1983

Houssaint,E. and Flajnik,M.: The role of Thymic Epitheelium in the acquisition of Tolerance. Immunology Today, Vol 11, No.10, pp.357-360,1986

Kappler,J.W., Roehm,N. and Marrack,P.: T Cell Tolerance by Clonal Elimination in the Thymus. Cell Vol 49:273-280, 1987.

Robertson,M.: Tolerance, restriction and the MLS enigma. Nature Vol. 332,March 1988.

Marrack,P, Lo,D., Brinster,R., Palmiter,R., Burkly,L. Flavell,R.H. and Kappler,J.: The effect of Thymus Environment on T Cell Development and Tolerance. Cell Vol 53, pp.627-634, May 1988.

DeFranco,A.L.: Fate of self-reactive B cells. Nature, Vol.334 Aug. 1988

Von Boehmer,H. and Kisielow,P.: Self-Nonself Discrimination by T Cells. Science Vol 248, pp1369-1372, June,1990

Ramsdell,F. and Fowlkes,B.J.: Clonal Deletion Versus Clonal Anergy: The Role Of The Thymus in inducing self tolerance. Science Vol 248, pp. 1342-1348, June,1990

Webb,S., Morris,C. and Sprent,J.: Extrathymic Tolerance of Mature T cells: clonal eliminatio as a consequence of immunity. Cell Vol.63 pp 1249-1256, Dec.1990

Schwartz,R.H.: A Cell Culture Model For T Lymphocyte Clonal Anergy. Science Vol 248, pp1349-1356, June, 1990

Sprent,J., Gao,E.K. and Webb, S.R.: T Cell Reactivity to MHC Molecules: Immunity versus Tolerance. Science Vol 248, pp1357-1363, June, 1990

Taguchi,O, Takahashi,T. and Nishizuka,Y.: Self-Tolerance and Localized Autoimmunity. Current Opinion in Immunology 2: 576-581, 1990

Sinha,A.A., Lopez,T. and McDevitt,H.O.: Autoimmune Diseases: The Failure of Self-Tolerance. Science Vol 248, pp1380-1388, June,1990

Goodnow,C.C., Adelstein,S. and Basten,A. The need for Central and peripheral tolerance in the B cell repertoire.Science Vol 248, pp. 1373-1379, June, 1990

Von Boehmer,H. and Kisielow,P.: How the immune System learns about self. Scientific American, pp 50-59 Oct.1991

Finkel,T.H., Kappler,J.W. and Marrack,P.C: Immature thymocytes are protected from deletion early in ontogeny. Proc. Natl. Acad. Sci. USA Vol 89, pp 3372-3374, April 1992.

6. Autoinmunidad

Klinman,D.M. and Steinberg,A.D.: Idiotipy and Autoimmunity. Arthritis and Rheumatism Vol.29,No.6 pp 768-773 June.1986

Oldstone,M.B.A.: Molecular Mimicry and autoimmune disease. Cell Vol
50,pp.819-820,Sept. 1987.

Kantor,F.S. : Autoinmunidad: trastorno de disregulación.
Hospital Practice (Ed. Español) Vol. 4 Num.1 pp. 44-57, Enero 1989

Hess, E.V. Artritis reumatoide complicada con vasculitis. Hospital Practice (ED.Español) Vol 4, 48-59, Abril 1989 :

Balow,J.E.: El lupus como enfermedad renal. Hospital Practice (ED.Español) Vol 4, Num.3, pp. 39-54, Marzo 1989.

Abramson,S.B. y Weissmann, G.: Productos de Fragmentación del complemento en la patogenia del Lupus Eritematoso Sistémico.
Hospital Practice (ED.Español) Vol 4, Num 6.pp. 41-55,Junio/Julio 1989.

Atkinson, M.A. and Maclaren, N.K.: What causes Diabetes? Scientific American Vol.263,No.1, pp.42-49, July 1990

Rennie,J.: The Body against itself. Scientific American Vol 263 No.6, pp.76-85, Dec.1990.

Pisetsky,D.S., Grudier,J.P. and Gilkeson,G.S.: A role for immunogenic DNA in the pathogenesis of Systemic Lupus Erythematosus. Arthritis and Rheumatism Vol.33, No.2 Feb. 1990

Firestein,G.S. and Zvaifler,N.J.: How Important are T cells in Chronic Rheumatoid Synovitis. Arthritis and Rheumatism Vol. 33, No.6 pp. 768-773 June.1990

Marx,J.: Taming Rogue Immune Reactions. Science Vol. 249 pp
246-249.July 1990

Nepom,G.T.: MHC Class-II Molecules and Autoimmunity. Annu. Rev. Immunol Vol.9,pp 493-525, 1991.

Klareskog,L.,Ronnelid,J.,Gudmundsson,S. and Karlsson-Parra,A.: Rheumatoid Arthritis. Current Opinion in Immunology 3:912-916, 1991

Pisetsky,D.S.: Systemic Lupus Erithematosus. Current Opinion in Immunology 3:917-923, 1991

Karp,S.L., Albert,S.E. and Neilson,E.G.: The Nephritogenic immune Response. Current Opinion in Immunology 3:906-911,1991

Ehrenstein,M. and Isenberg,D.: Autoimmunity associated with infection: leprosy, acute rheumatic fever and Lyme disease. Current Opinion in Immunology 3:930-935, 1991

Cohen,I. and Weigert,M. Autoimmunity.Current Opinion in Immunology 3:887,1991

Kumar,V. and Sercarz,E.E.: Regulation in Autoimmunity. Current Opinion in Immunology 3:888-895, 1991

Dinarello,C.A.: Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases. Current Opinion in Immunology 3:941-948, 1991

Lopate,G. and Pestronk,A.: Miastenia grave autoinmune. Hospital Practice (ED.Español) Vol 8,Num.6. 5-19,Junio-Julio,1993

Friedmann,S.M., Tumang,J.R. and Crow,M.K.: Microbial Superantigens as Etiopathogenic Agents in Autoimmunity. Reumatic Disease Clinics of North America Vol.19,No.1, Feb.1993

7. Inmunodeficiencias:

Gupta, S.: New concepts in immunodeficiency diseases.
Immunology Today,Vol 11,No. 10,pp.344-346 ,1990.